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In silico analysis of single nucleotide polymorphisms (SNPs) in human C-C chemokine receptor type five (CCR5) gene

2020-11-16

Abstract excerpt

<h4>Introduction</h4> Chemokines are small transmembrane proteins with immune surveillance and immune cell recruitment functions. the expression of CCR5 gene affects virus production and viral load(1). The CCR5 gene contains two introns, three exons, and two promoters, and it is necessary as a co-receptor for the entry of the macrophage-tropic HIV strains. Mutations in the coding region of CCR5 affect the protein...

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Literature Corpus work
53ca9c50-e69e-5484-8010-082067465b89
DOI
10.1101/2020.11.14.382739
Open publication

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