Article
Distribution of the CCR5 gene 32-basepair deletion in 11 Chinese populations.
Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur - 1 Sept 2002
Zhang Chunyu, Fu Songbin, Xue Yali, Wang Qi, Huang Xiaoyi, Wang Baiqiu, Liu An, Ma Linlin, Yu Yang, Shi Rongqian, Lv Fuqu, Shi Zhongcheng, Zhang Yu, Cheng Wenhong, Ai Qionghua, Xu Fang, Huang Chengbin, Chen Baibin, Kang Xianghua, Sun Yanyang, Zhang Guiyin, Li Pu
Abstract excerpt
A mutant allele of the chemokine receptor gene CCR5 bearing a 32-basepair deletion (delta 32CCR5) could increase the resistance to HIV-1 infection or delayed progression to AIDS. The frequency of this mutation is higher in Europeans than in Asians. To investigate the distribution of this polymorphism in China, 715 individuals from 11 Chinese populations were screened by PCR, including the Han and 10 other ethnic...
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