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Article

Differential enhancement of a cutaneous HPV promoter by DeltaNP63alpha, Jun and mutant p53.

Cell cycle (Georgetown, Tex.) - 1 May 2005

Fei Jian-Wei, Wei Quan-Xiang, Angel Peter, de Villiers Ethel-Michele

Abstract excerpt

The mechanism through which cutaneous papillomaviruses induce lesions is largely unknown. Ectopic expression of the DeltaNp63alpha isoform highly increased the viral promoter activity. The co-expression of c-Jun mediated and increased the DeltaNp63alpha activity by binding to the AP-1 site in an enhancer region of the HPV 20 URR. This strong activation by DeltaNp63alpha is diminished in the presence of wtp53 and...

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Source

Identifiers

PMID: 15846070
DOI: 10.4161/cc.4.5.1653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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