Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p63 Is Necessary for the Activation of Human Papillomavirus Late Viral Functions upon Epithelial Differentiation

30 Jun 2011

Abstract excerpt

The late phase of the human papillomavirus (HPV) life cycle is linked to epithelial differentiation, and we investigated the factors that regulate this process. One potential regulator is p63, a member of the p53 family of proteins, which modulates epithelial development, as well as proliferation capability, in stem cells. In this study, we examined the role of p63 in the HPV life cycle using a lentiviral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cervical Cancer and HPV Research
Share to Molecular Biology Techniques and Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21715473
DOI: 10.1128/jvi.00750-11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p63 Is Necessary for the Activation of Human Papillomavirus Late Viral Functions upon Epithelial DifferentiationPMID 21715473Read ↗

Tumor-Specific p73 Up-regulation Mediates p63 Dependence in Squamous Cell CarcinomaSemantic proximity Read ↗

Dysregulated ΔNp63α inhibits expression of Ink4a/arf, blocks senescence, and promotes malignant conversion of keratinocytes.Semantic proximity Read ↗

p63: Defining roles in morphogenesis, homeostasis, and neoplasia of the epidermisSemantic proximity Read ↗

Induced multipotency in adult keratinocytes through down-regulation of <i>ΔNp63</i> or <i>DGCR8</i>Semantic proximity Read ↗

TAp63 and DeltaNp63 in cancer and epidermal development.Semantic proximity Read ↗

p63-related signaling at a glanceSemantic proximity Read ↗

Manipulation of Epithelial Differentiation by HPV OncoproteinsSemantic proximity Read ↗

p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and CancerSemantic proximity Read ↗

Distinct interactors define the p63 transcriptional signature in epithelial development or cancerSemantic proximity Read ↗

ΔNp63α Repression of the <i>Notch1</i> Gene Supports the Proliferative Capacity of Normal Human Keratinocytes and Cervical Cancer CellsSemantic proximity Read ↗

The Roles of p63 in CancerSemantic proximity Read ↗

Identification and functional characterization of two new transcriptional variants of the human p63 geneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.