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Article

Intersection of the p63 and NF‐κB pathways in epithelial homeostasis and disease

8 Jul 2019

Abstract excerpt

Overexpression of ΔNp63α, a member of the p53/p63/p73 family of transcription factors, is a molecular attribute of human squamous cancers of the head and neck, lung and skin. The TP63 gene plays important roles in epidermal morphogenesis and homeostasis, regulating diverse biological processes including epidermal fate decisions and keratinocyte proliferation and survival. When overexpressed experimentally in...

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PMID: 31286584
DOI: 10.1002/mc.23081

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