Article
Properties of the transmission-disequilibrium test in the presence of inbreeding.
Genetic epidemiology - 1 Feb 2002
Génin Emmanuelle, Todorov Alexandre A, Clerget-Darpoux Françoise
Abstract excerpt
Family-based association tests such as the transmission-disequilibrium test (TDT), which compare alleles transmitted and non-transmitted from parents to affected offspring, are widely used to detect the role of genetic risk factors in diseases. These methods have the advantage of being robust to population stratification and are thus believed to be valid whatever the population context. In different studies of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
