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Article

New concepts for distinguishing the hidden patterns of linkage disequilibrium which underlie association between genotypes and complex phenotypes.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Apr 2005

Wicks Jacqueline, Treloar Susan A, Martin Nicholas G, Duffy David L

Abstract excerpt

A disappointing feature of conventional methods for detecting association between DNA variation and a phenotype of interest is that they tell us little about the hidden pattern of linkage disequilibrium (LD) with the functional variant that is actually responsible for the association. This limitation applies to case-control studies and also to the transmission/disequilibrium test (TDT) and other family-based...

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PMID: 15901471
DOI: 10.1375/1832427053738737

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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