Article
Low rate of microsatellite instability in young patients with adenomas: reassessing the Bethesda guidelines.
The American journal of gastroenterology - 1 May 2005
Velayos Fernando S, Allen Brian A, Conrad Peggy G, Gum James, Kakar Sanjay, Chung Daniel C, Truta Brindusa, Sleisenger Marvin H, Kim Young S, Terdiman Jonathan P
Abstract excerpt
BACKGROUND AND AIM: Screening adenomas for microsatellite instability (MSI) in patients younger than 40 yr of age has been recommended by the Bethesda Guidelines as a means of identifying patients at risk for hereditary nonpolyposis colorectal cancer (HNPCC). We sought to determine the rate of MSI in adenomas removed from individuals under 40 yr of age over a 5-yr period in a university general gastroenterology...
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