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Article

Dysregulation of hedgehog signalling predisposes to synovial chondromatosis.

The Journal of pathology - 1 Jun 2005

Hopyan Sevan, Nadesan Puviindran, Yu Chunying, Wunder Jay, Alman Benjamin A

Abstract excerpt

Synovial chondromatosis is a condition affecting joints in which metaplastic cartilage nodules arise from the synovium, causing pain, joint dysfunction, and ultimately joint destruction. Because dysregulation of hedgehog signalling is a feature of several benign cartilaginous tumours, expression of the hedgehog target genes PTC1 and GLI1 was examined in this study in samples from human synovial chondromatosis....

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Source

Identifiers

PMID: 15834844
DOI: 10.1002/path.1761

Genes

GLI1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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