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Peripheral chondrosarcoma progression is accompanied by decreased Indian Hedgehog signalling

5 Jun 2006

Abstract excerpt

Hedgehog (HH) signalling is important for specific developmental processes, and aberrant, increased activity has been described in various tumours. Disturbed HH signalling has also been implicated in the hereditary syndrome, Multiple Osteochondromas. Indian Hedgehog (IHH), together with parathyroid hormone-like hormone (PTHLH), participates in the organization of growth plates in long bones. PTHLH signalling is...

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PMID: 16755518
DOI: 10.1002/path.2008

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