Article
Embryonic fibroblasts from mice lacking Tgif were defective in cell cycling.
Molecular and cellular biology - 1 Jun 2006
Mar Lynn, Hoodless Pamela A
Abstract excerpt
Holoprosencephaly (HPE) is the most common structural anomaly of the human brain, resulting from incomplete cleavage of the developing forebrain during embryogenesis. Haploinsufficient mutations in the TG-interacting factor (TGIF) gene were previously identified in a subset of HPE families and sporadic patients, and this gene is located within a region of chromosome 18 that is associated with nonrandom...
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