Article
Loss of the Tg737 protein results in skeletal patterning defects.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 May 2003
Zhang Qihong, Murcia Noel S, Chittenden Laura R, Richards William G, Michaud Edward J, Woychik Richard P, Yoder Bradley K
Abstract excerpt
Tg737 mutant mice exhibit pathologic conditions in numerous tissues along with skeletal patterning defects. Herein, we characterize the skeletal pathologic conditions and confirm a role for Tg737 in skeletal patterning through transgenic rescue. Analyses were conducted in both the hypomorphic Tg737(orpk) allele that results in duplication of digit one and in the null Tg737(delta2-3betaGal) allele that is an...
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