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Article

Leptin receptor gene variation predicts weight change in subjects with impaired glucose tolerance.

Obesity research - 1 Mar 2005

Zacharova Jelena, Chiasson Jean-Louis, Laakso Markku

Abstract excerpt

The leptin receptor (OB-R) gene is a promising candidate gene for type 2 diabetes, because leptin and its receptor play an important role in insulin secretion and the development of obesity. Therefore, we studied whether the pentanucleotide insertion polymorphism of the 3'-untranslated region (3'UTR) of the OB-R gene has an influence on the conversion from impaired glucose tolerance (IGT) to type 2 diabetes in...

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Identifiers

PMID: 15833934
DOI: 10.1038/oby.2005.52

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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