Article
Effects of leptin receptor gene 3'-untranslated region polymorphism on metabolic profiles in young Japanese men.
Journal of atherosclerosis and thrombosis - 1 Jan 2004
Nishikai Kanako, Hirose Hiroshi, Ishii Tatsuya, Hayashi Matsuhiko, Saito Ikuo, Saruta Takao
Abstract excerpt
We investigated the effects of leptin receptor gene 3'-untranslated region (3'-UTR) polymorphism on clinical and metabolic parameters in 221 young Japanese men aged 21 to 28 years. The polymerase chain reaction-restriction fragment length polymorphism method was used to identify a pentanucleotide (CTTTA) insertion in 3'-UTR of the leptin receptor gene. Body mass index, blood pressure, plasma glucose, insulin,...
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