Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in the leptin receptor gene, leptin, and weight gain in young Dutch adults.

Obesity research - 1 Mar 2003

van Rossum Caroline T M, Hoebee Barbara, van Baak Marleen A, Mars Monica, Saris Wim H M, Seidell Jacob C

Abstract excerpt

OBJECTIVE: To investigate the association between leptin levels, polymorphisms in the leptin receptor (LEPR) gene, and weight gain. RESEARCH METHODS AND PROCEDURES: From two large prospective cohorts in The Netherlands (n = 17,500), we compared the baseline leptin of 259 subjects who had gained an average of 12.6 kg (range 5.5 to 33 kg) with 277 subjects who kept stable weight (range -2.6 to 3.1 kg) after a mean...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arginine
Share to Glutamine
Share to Leptin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lysine

Share to Netherlands

Share to Receptors, Leptin

Share to Sex Characteristics

Share to Weight Gain

Source

Identifiers

PMID: 12634434
DOI: 10.1038/oby.2003.51

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in the leptin receptor gene, leptin, and weight gain in young Dutch adults.PMID 12634434Read ↗

Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish Diabetes Prevention Study.Semantic proximity Read ↗

Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study.Semantic proximity Read ↗

The Q223R Polymorphism of the Leptin Receptor Gene as a Predictor of Weight Gain in Childhood Obesity and the Identification of Possible Factors Involved.Semantic proximity Read ↗

Polymorphisms in the leptin receptor gene, body composition and fat distribution in overweight and obese women.Semantic proximity Read ↗

LEPR gene polymorphisms: associations with overweight, fat mass and response to diet in women.Semantic proximity Read ↗

Leptin receptor gene polymorphisms are associated with adiposity and metabolic alterations in Brazilian individualsSemantic proximity Read ↗

Genetic factors as predictors of weight gain in young adult Dutch men and women.Semantic proximity Read ↗

Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain.Semantic proximity Read ↗

Leptin Receptor Lys656Asn Polymorphism Is Associated with Decreased Leptin Response and Weight Loss Secondary to a Lifestyle Modification in Obese PatientsSemantic proximity Read ↗

Leptin receptor gene K656N polymorphism is associated with low body fat levels and elevated high-density cholesterol levels in Mexican children and adolescents.Semantic proximity Read ↗

Changes in Body Mass Index, Leptin, and Leptin Receptor Polymorphisms and Breast Cancer Risk.Semantic proximity Read ↗

Genetic variation and obesity in Australian women: a prospective study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.