Article
Identification of Incidental Sequence Polymorphisms and Absence of the <i>db/db</i> Mouse and <i>fa/fa</i> Rat Mutations
1 Jul 1996
Abstract excerpt
Leptin-receptor gene expression in hypothalamic tissue from lean and obese humans was examined. The full-length leptin receptor, that is believed to transmit the leptin signal, is expressed in human hypothalamus. There was no difference in the amount of leptin-receptor mRNA In seven lean (BMI 23.3 +/- 0.9 kg/m2) and eight obese (BMI 36.9 +/- 1.5) subjects as determined by reverse transcription-polymerase chain...
