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Article

The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication.

Journal of virology - 1 May 2005

Tang Hong, Delgermaa Luvsanjav, Huang Feijun, Oishi Naoki, Liu Li, He Fang, Zhao Liansan, Murakami Seishi

Abstract excerpt

The role and functional domain of hepatitis B virus (HBV) X protein (HBx) in regulating HBV transcription and replication were investigated with a transient transfection system in the human hepatoma cell line HepG2 using wild-type or HBx-minus HBV genome constructs and a series of deletion or mutation HBx expression plasmids. We show here that HBx has augmentation effects on HBV transcription and replication as a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Protein Structure, Tertiary

Share to Trans-Activators

Share to Transcription, Genetic

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Share to Viral Regulatory and Accessory Proteins

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Source

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Identifiers

PMID: 15827169
DOI: 10.1128/JVI.79.9.5548-5556.2005
PMCID: PMC1082733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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