Article
Transactivating function and expression of the x gene of hepatitis B virus.
Journal of hepatology - 1 Jul 1995
Renner M, Haniel A, Bürgelt E, Hofschneider P H, Koch W
Abstract excerpt
BACKGROUND/AIMS: The x gene of hepatitis B virus encodes a transactivating factor of 154 amino acids, termed HBx, which stimulates transcription of multiple viral and cellular genes. The transactivating function is probably associated with a tumorigenic potential of HBx, since x gene sequences, encoding functional HBx, have been repeatedly found integrated into the genome of liver carcinoma cells. METHODS: To...
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