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Article

Molecular mechanism of hepatitis B virus X protein function in hepatocarcinogenesis

1 Jan 2015

Abstract excerpt

Many factors are considered to contribute to hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC), including products of HBV, HBV integration and mutation, and host susceptibility. HBV X protein (HBx) can interfere with several signaling pathways associated with cell proliferation and invasion, and HBx C-terminal truncation has been suggested to impact the development of HCC. This review focuses on...

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PMID: 26478665
DOI: 10.3748/wjg.v21.i38.10732

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