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Article

Human hepatitis virus X gene encodes a regulatory domain that represses transactivation of X protein.

1 May 1994

Abstract excerpt

The human hepatitis B virus (HBV) X gene seems to be essential for establishment of viral infection, and the X gene product, HBx, transactivates virus and host genes through a wide variety of cis-elements, whereas regulation of HBx has not been fully understood. We found that transactivation-negative HBx mutants truncated at the C-terminal portion specifically repressed the HBx transactivation in trans. The...

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Identifiers

PMID: 8195148
DOI: 10.1016/s0021-9258(17)36581-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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