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Article

Molecular functions and biological roles of hepatitis B virus x protein

14 Sept 2006

Abstract excerpt

Chronic infection of hepatitis B virus (HBV) is one of the major causes of hepatocellular carcinoma (HCC) in the world. Hepatitis B virus X protein (HBx) has been long suspected to be involved in hepatocarcinogenesis, although its oncogenic role remains controversial. HBx is a multifunctional regulator that modulates transcription, signal transduction, cell cycle progress, protein degradation pathways, apoptosis,...

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Identifiers

PMID: 16984372
DOI: 10.1111/j.1349-7006.2006.00299.x

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