Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis B virus X protein interferes with cellular DNA repair.

Journal of virology - 1 Jan 1998

Becker S A, Lee T H, Butel J S, Slagle B L

Abstract excerpt

The hepatitis B virus X protein (HBx) is a broadly acting transactivator implicated in the development of liver cancer. Recently, HBx has been reported to interact with several different cellular proteins, including our report of its binding to XAP-1, the human homolog of the simian repair protein UVDDB. In the present study, several HBx mutants were used to localize the minimal domain of HBx required for binding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to DNA-Binding Proteins
Share to DNA Repair

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Viral

Share to Mutation

Share to Protein Binding

Share to Tumor Cells, Cultured

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 9420223
DOI: 10.1128/JVI.72.1.266-272.1998
PMCID: PMC109372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis B virus X protein interferes with cellular DNA repair.PMID 9420223Read ↗

Hepatitis B virus X protein inhibits nucleotide excision repairSemantic proximity Read ↗

Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutants.Semantic proximity Read ↗

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3.Semantic proximity Read ↗

Hepatitis B Virus X Protein: Structure, Function and BiologySemantic proximity Read ↗

Hepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death.Semantic proximity Read ↗

Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls.Semantic proximity Read ↗

Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH.Semantic proximity Read ↗

Hepatitis B virus X protein enhances NFκB activity through cooperating with VBP1Semantic proximity Read ↗

Hepatitis B Viral Protein HBx and the Molecular Mechanisms Modulating the Hallmarks of Hepatocellular Carcinoma: A Comprehensive ReviewSemantic proximity Read ↗

Hepatitis B Virus X Protein and HepatocarcinogenesisSemantic proximity Read ↗

Human hepatitis virus X gene encodes a regulatory domain that represses transactivation of X protein.Semantic proximity Read ↗

Interaction of mutant hepatitis B X protein with p53 tumor suppressor protein affects both transcription and cell survival.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.