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Article

Enhancement of hepatitis B virus replication by its X protein in transgenic mice.

Journal of virology - 1 Mar 2002

Xu Zhenming, Yen T S Benedict, Wu Lanying, Madden Charles R, Tan Wenjie, Slagle Betty L, Ou Jing-hsiung

Abstract excerpt

Hepatitis B virus (HBV) X gene encodes a multifunctional protein that can regulate cellular signaling pathways, interact with cellular transcription factors, and induce hepatocellular oncogenesis. In spite of its diverse activities, the precise role of the X protein in the viral life cycle of HBV remains unclear. To investigate this question, we have produced transgenic mice that carry either the wild-type HBV...

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Share to Gene Expression Regulation, Viral
Share to Hepatitis B virus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Transgenic

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Source

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Identifiers

PMID: 11836439
DOI: 10.1128/jvi.76.5.2579-2584.2002
PMCID: PMC153824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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