Hepatitis B virus X protein inhibits nucleotide excision repair

Abstract excerpt

Hepatocellular carcinoma (HCC) is a common tumor worldwide and ranks as one of the 4 most prevalent malignant diseases of adults in Asia and sub-Saharan Africa. More than 250,000 cases of HCC are diagnosed each year, and less than 3% of these patients will survive 5 or more years (Feitelson and Duan, 1997). Chronic infection with hepatitis B virus (HBV), ingestion of aflatoxin B1 (AFB1)-contaminated foods,...

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