Article
Assessing maternal genetic associations: a comparison of the log-linear approach to case-parent triad data and a case-control approach.
Epidemiology (Cambridge, Mass.) - 1 May 2005
Starr Jacqueline R, Hsu Li, Schwartz Stephen M
Abstract excerpt
BACKGROUND: In utero exposures, including maternal phenotypes, are potential risk factors for both early-onset and adult-onset diseases. Two alternative study designs use maternal genotypes at polymorphic loci as biomarkers of an offspring's in utero exposure: (1) a traditional case-control study with logistic regression analysis, in which cases, controls, and mothers of both types of subjects are genotyped; and...
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