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Article

Analysis of genetic interactions involving maternal and offspring genotypes at different Loci: power simulation and application to testicular cancer.

Genetic epidemiology - 1 Sept 2012

Nsengimana Jérémie, Barrett Jennifer H

Abstract excerpt

The analyses of genetic interaction between maternal and offspring genotypes are usually conducted considering a single locus. Here, we propose testing maternal × offspring (M×O) and maternal × maternal (M×M) genotype interactions involving two unlinked loci. We reformulate the log-linear approach of analyzing cases and their parents (family trios) to accommodate two loci, fit fuller models to avoid confounding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22740241
DOI: 10.1002/gepi.21655
PMCID: PMC3504980

Genes

KITLG
SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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