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Article

The use of case-parent triads to study joint effects of genotype and exposure.

American journal of human genetics - 1 Jan 2000

Umbach D M, Weinberg C R

Abstract excerpt

Most noninfectious disease is caused by low-penetrance alleles interacting with other genes and environmental factors. Consider the simple setting where a diallelic autosomal candidate gene and a binary exposure together affect disease susceptibility. Suppose that one has genotyped affected probands and their parents and has determined each proband's exposure status. One proposed method for assessment of...

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Identifiers

PMID: 10631155
DOI: 10.1086/302707
PMCID: PMC1288330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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