Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRCA2: breaks, mistakes and failed separations.

Trends in molecular medicine - 1 Apr 2005

Rudkin Teresa M, Foulkes William D

Abstract excerpt

BRCA2 was identified in 1995, one year after BRCA1. In terms of knowledge of the function of its product, BRCA2 has remained the less well-characterised gene. Both BRCA1 and BRCA2 are closely implicated in the repair of double-strand breaks in DNA by homologous recombination, but beyond that a function for BRCA2 has been hard to discern. A recent study has extended the function of BRCA2 to the regulation of cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein
Share to Cytokinesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RAD51 gene

Share to Genes, BRCA2

Share to Mutation

Share to Neoplasms

Share to Phenotype

Source

Identifiers

PMID: 15823750
DOI: 10.1016/j.molmed.2005.02.003

Genes

BRCA2
BRCA1
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRCA2: breaks, mistakes and failed separations.PMID 15823750Read ↗

DNA recombination, chromosomal stability and carcinogenesis: insights into the role of BRCA2.Semantic proximity Read ↗

Mechanisms underlying genome maintenance and tumour suppression by BRCA2Semantic proximity Read ↗

The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability.Semantic proximity Read ↗

A protective role for BRCA2 at stalled replication forks.Semantic proximity Read ↗

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition.Semantic proximity Read ↗

BRCA mutations and reproduction.Semantic proximity Read ↗

BRCA1 and BRCA2 in breast cancer predisposition and recombination control.Semantic proximity Read ↗

Clues to the function of the tumour susceptibility gene BRCA2.Semantic proximity Read ↗

Chromosome stability, DNA recombination and the BRCA2 tumour suppressor.Semantic proximity Read ↗

Structure and mechanism of the BRCA2 tumour suppressorSemantic proximity Read ↗

Who's who in human recombination: BRCA2 and RAD52.Semantic proximity Read ↗

Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.