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Article

Chromosome stability, DNA recombination and the BRCA2 tumour suppressor.

Current opinion in cell biology - 1 Jun 2001

Venkitaraman A R

Abstract excerpt

The BRCA2 tumour suppressor works in DNA recombination and repair pathways to preserve genome integrity. Recent progress provides fresh insights into its role as a regulator of the Rad51 recombination protein, underpinning a model in which BRCA2's involvement in chromosome stability and tumour suppression arises from its participation in recombinational processes essential for DNA replication.

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Share to BRCA2 Protein
Share to Cell Transformation, Neoplastic
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11343905
DOI: 10.1016/s0955-0674(00)00217-9

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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