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Article

BRCA mutations and reproduction.

Fertility and sterility - 1 Jan 2018

Daum Hagit, Peretz Tamar, Laufer Neri

Abstract excerpt

Deleterious mutations in BRCA1 or BRCA2 genes have long been recognized as independent risk factors, mostly for breast and ovarian cancer. Numerous studies have evaluated the molecular processes involving these genes, the pathophysiology of BRCAness, follow up options and modes of prophylaxis. The fertility of BRCA carriers, however, has not been widely investigated. The aim of the present work is to review the...

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Source

Identifiers

PMID: 29307397
DOI: 10.1016/j.fertnstert.2017.12.004

Genes

BRCA1
BRCA2

Provenance

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