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Article

BRCA1 and BRCA2 in breast cancer predisposition and recombination control.

Journal of mammary gland biology and neoplasia - 1 Jul 2004

Scully Ralph, Xie Anyong

Abstract excerpt

Hereditary predisposition to breast and ovarian cancer is determined in large part by loss-of-function mutations in one of two genes, BRCA1 and BRCA2 . Early discoveries that the two genes function in the control of homologous recombination and the prevention of genomic instability have been strongly supported by subsequent work. Our aim here is to highlight new advances in the study of BRCA1 and BRCA2 , and to...

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Share to Breast Neoplasms
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Share to Genes, BRCA1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA2

Share to Genetic Predisposition to Disease

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Share to Ovarian Neoplasms

Share to Recombination, Genetic

Source

Identifiers

PMID: 15557797
DOI: 10.1023/B:JOMG.0000048771.93906.3e

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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