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Article

Identification of subtypes of CYP2D gene rearrangements among carriers of CYP2D6 gene deletion and duplication.

Clinical chemistry - 1 Jun 2005

Ledesma María C, Agúndez José A G

Abstract excerpt

BACKGROUND: Cytochrome P450 2D6 (CYP2D6) is one of the best-known polymorphic drug-metabolizing enzymes. Rapidly evolving genotyping techniques permit the identification of single-nucleotide polymorphisms (SNPs) and thereby a prediction of individual metabolic capacities for CYP2D6 substrates. A considerable part of interindividual variability in CYP2D6 enzyme activity, however, is not related to SNPs but to gene...

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Source

Identifiers

PMID: 15817819
DOI: 10.1373/clinchem.2004.046326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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