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Article

Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians.

Pharmacogenetics - 1 Jun 1997

McLellan R A, Oscarson M, Seidegård J, Evans D A, Ingelman-Sundberg M

Abstract excerpt

The polymorphic cytochrome P450 2D6 (CYP2D6) causing poor, extensive or ultrarapid metabolism of several clinically important drugs exhibits pronounced interethnic variation. Ultrarapid metabolism is caused by multiple copies of active CYP2D6 genes and recently 29% of an Ethiopian population has been shown to carry duplicated or multiduplicated CYP2D6 genes, whereas the corresponding frequency in other black,...

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Source

Identifiers

PMID: 9241658
DOI: 10.1097/00008571-199706000-00003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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