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Article

CYP2D6: novel genomic structures and alleles.

Pharmacogenetics and genomics - 1 Oct 2009

Kramer Whitney E, Walker Denise L, O'Kane Dennis J, Mrazek David A, Fisher Pamela K, Dukek Brian A, Bruflat Jamie K, Black John L

Abstract excerpt

OBJECTIVE: CYP2D6 is a polymorphic gene. It has been observed to be deleted, to be duplicated and to undergo recombination events involving the CYP2D7 pseudogene and surrounding sequences. The objective of this study was to discover the genomic structure of CYP2D6 recombinants that interfere with clinical genotyping platforms that are available today. METHODS: Clinical samples containing rare homozygous CYP2D6...

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Identifiers

PMID: 19741566
DOI: 10.1097/FPC.0b013e3283317b95
PMCID: PMC2862371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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