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Article

Behavioural phenotypes of hypomorphic KCC2-deficient mice.

The European journal of neuroscience - 1 Mar 2005

Tornberg Janne, Voikar Vootele, Savilahti Harri, Rauvala Heikki, Airaksinen Matti S

Abstract excerpt

Hyperpolarizing fast inhibitory neurotransmission by gamma-aminobutyric acid and glycine requires an efficient chloride extrusion mechanism in postsynaptic neurons. A major effector of this task in adult animals is the potassium-chloride co-transporter KCC2 that is selectively and abundantly expressed postsynaptically in most CNS neurons. Yet, the role of KCC2 in adult brain at the systems level is poorly known....

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Identifiers

PMID: 15813942
DOI: 10.1111/j.1460-9568.2005.03959.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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