Article
Toll-like receptor signaling pathway variants and prostate cancer mortality.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2009
Stark Jennifer R, Wiklund Fredrik, Grönberg Henrik, Schumacher Fredrick, Sinnott Jennifer A, Stampfer Meir J, Mucci Lorelei A, Kraft Peter
Abstract excerpt
An understanding of factors associated with prostate cancer (PCa) mortality is increasingly important given the biological heterogeneity of disease. Previous studies have shown that genetic variation in the Toll-like receptor (TLR) signaling pathway is associated with PCa incidence, but any role in progression and mortality is unclear. Among 1,252 PCa cases from the Cancer Prostate in Sweden study, we conducted...
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