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Article

Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development.

The Journal of biological chemistry - 20 May 2005

Yanagi Ken-ichiro, Mizuno Takeshi, Tsuyama Takashi, Tada Shusuke, Iida Yumi, Sugimoto Asako, Eki Toshihiko, Enomoto Takemi, Hanaoka Fumio

Abstract excerpt

Cdt1 is an essential component for the assembly of a pre-replicative complex. Cdt1 activity is inhibited by geminin, which also participates in neural development and embryonic differentiation in many eukaryotes. Although Cdt1 homologues have been identified in organisms ranging from yeast to human, geminin homologues had not been described for Caenorhabditis elegans and fungi. Here, we identify the C. elegans...

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PMID: 15811859
DOI: 10.1074/jbc.C500070200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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