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Article

Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function.

American journal of respiratory and critical care medicine - 1 Jul 2005

Simpson Angela, Maniatis Nikolas, Jury Francine, Cakebread Julie A, Lowe Lesley A, Holgate Stephen T, Woodcock Ashley, Ollier William E R, Collins Andrew, Custovic Adnan, Holloway John W, John Sally L

Abstract excerpt

RATIONALE: Asthma commonly originates in early life in association with impaired lung function, which tracks to adulthood. OBJECTIVES: Within the context of a prospective birth cohort study, we investigated the association between single nucleotide polymorphisms (SNPs) in a disintegrin and metalloprotease 33 (ADAM33) gene and early-life lung function. METHODS: Children were genotyped for 17 SNPs in ADAM33. Lung...

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Source

Identifiers

PMID: 15805180
DOI: 10.1164/rccm.200412-1708OC

Genes

ADAM33
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function.PMID 15805180Read ↗

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