Article
ADAM33 polymorphisms and phenotype associations in childhood asthma.
The Journal of allergy and clinical immunology - 1 Jun 2004
Raby Benjamin A, Silverman Edwin K, Kwiatkowski David J, Lange Christoph, Lazarus Ross, Weiss Scott T
Abstract excerpt
BACKGROUND: A disintegrin and metalloproteinase (ADAM) 33 has been implicated as an asthma susceptibility gene by using a positional cloning approach. However, genetic linkage of asthma phenotypes to chromosome 20p13 (the location of ADAM33) has not been observed in most asthma genome scans, and it is unclear whether these associations with ADAM33 are broadly generalizable. OBJECTIVE: To examine whether ADAM33 is...
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