Article
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness.
Nature - 25 Jul 2002
Van Eerdewegh Paul, Little Randall D, Dupuis Josée, Del Mastro Richard G, Falls Kathy, Simon Jason, Torrey Dana, Pandit Sunil, McKenny Joyce, Braunschweiger Karen, Walsh Alison, Liu Ziying, Hayward Brooke, Folz Colleen, Manning Susan P, Bawa Alicia, Saracino Lisa, Thackston Michelle, Benchekroun Youssef, Capparell Neva, Wang Mei, Adair Ron, Feng Yun, Dubois JoAnn, FitzGerald Michael G, Huang Hui, Gibson René, Allen Kristina M, Pedan Alex, Danzig Melvyn R, Umland Shelby P, Egan Robert W, Cuss Francis M, Rorke Steuart, Clough Joanne B, Holloway John W, Holgate Stephen T, Keith Tim P
Abstract excerpt
Asthma is a common respiratory disorder characterized by recurrent episodes of coughing, wheezing and breathlessness. Although environmental factors such as allergen exposure are risk factors in the development of asthma, both twin and family studies point to a strong genetic component. To date, linkage studies have identified more than a dozen genomic regions linked to asthma. In this study, we performed a...
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