Article
ADAM33: a newly identified protease involved in airway remodelling.
Pulmonary pharmacology & therapeutics - 1 Jan 2006
Holgate Stephen T, Davies Donna E, Powell Rob M, Holloway John W
Abstract excerpt
Asthma is a complex disorder in which major genetic and environmental factors interact to both initiate the disease and modify its progression. While asthma is recognised as a disorder of the conducting airways characterised by Th2-directed inflammation, it is being increasingly apparent that alteration of the structural cells of the airways (airway remodelling) is also fundamental to disease chronicity and...
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