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Article

ADAM metallopeptidase domain 33 (ADAM33): identification and role in airways disease.

Drug news & perspectives - 1 Jan 2000

Holgate Stephen T

Abstract excerpt

Asthma is a common disorder of the airways which exhibit variable obstruction associated with hyperresponsiveness linked to altered smooth muscle. Although environmental factors are important in the origins and progression of asthma, it is a disorder with high heritability. The identification of ADAM33 (ADAM metallopeptidase domain 33, a disintegrin and metalloproteinase domain 33) as the first novel asthma gene...

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Source

Identifiers

PMID: 20697605
DOI: 10.1358/dnp.2010.23.6.1437242

Genes

ADAM33

Provenance

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Related research

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ADAM metallopeptidase domain 33 (ADAM33): identification and role in airways disease.PMID 20697605Read ↗

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ADAM33: a newly identified protease involved in airway remodelling.Semantic proximity Read ↗

Role of ADAM33 Gene and Associated Single Nucleotide Polymorphisms in AsthmaSemantic proximity Read ↗

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness.Semantic proximity Read ↗

Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations.Semantic proximity Read ↗

Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early lifeSemantic proximity Read ↗

ADAM33 expression in asthmatic airways and human embryonic lungs.Semantic proximity Read ↗

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