Article
EphB receptor tyrosine kinases control morphological development of the ventral midbrain.
Mechanisms of development - 1 Apr 2005
Altick Amy L, Dravis Christopher, Bowdler Tracey, Henkemeyer Mark, Mastick Grant S
Abstract excerpt
EphB receptor tyrosine kinases and ephrin-B ligands regulate several types of cell-cell interactions during brain development, generally by modulating the cytoskeleton. EphB/ephrinB genes are expressed in the developing neural tube of early mouse embryos with distinct overlapping expression in the ventral midbrain. To test EphB function in midbrain development, mouse embryos compound homozygous for mutations in...
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