Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries.

Genes & development - 15 Sept 2010

Bush Jeffrey O, Soriano Philippe

Abstract excerpt

Mutations in the X-linked human EPHRIN-B1 gene result in cleft palate and other craniofacial anomalies as part of craniofrontonasal syndrome (CFNS), but the molecular and developmental mechanisms by which ephrin-B1 controls the underlying developmental processes are not clear. Here we demonstrate that ephrin-B1 plays an intrinsic role in palatal shelf outgrowth in the mouse by regulating cell proliferation in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Proliferation
Share to Craniofacial Abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Mitogen-Activated Protein Kinase Kinases

Share to Morphogenesis

Share to Palate

Share to Syndrome

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 20844017
DOI: 10.1101/gad.1963210
PMCID: PMC2939368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries.PMID 20844017Read ↗

Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome.Semantic proximity Read ↗

Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome.Semantic proximity Read ↗

Ephrin-B1 forward and reverse signaling are required during mouse development.Semantic proximity Read ↗

Aberrant cell segregation in the craniofacial primordium and the emergence of facial dysmorphology in craniofrontonasal syndrome.Semantic proximity Read ↗

Aberrant cell segregation in craniofacial primordia and the emergence of facial dysmorphology in craniofrontonasal syndromeSemantic proximity Read ↗

Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism.Semantic proximity Read ↗

Control of skeletal patterning by ephrinB1-EphB interactions.Semantic proximity Read ↗

EPH Receptor Tyrosine Kinases Regulate Epithelial Morphogenesis and Phosphorylate the PAR-3 Scaffold Protein to Modulate Downstream Signaling NetworksSemantic proximity Read ↗

The impact of CFNS-causing EFNB1 mutations on ephrin-B1 function.Semantic proximity Read ↗

EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells.Semantic proximity Read ↗

Pou3f4-mediated regulation of ephrin-b2 controls temporal bone development in the mouse.Semantic proximity Read ↗

Chondrocytic ephrin B2 promotes cartilage destruction by osteoclasts in endochondral ossification.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.