Article
Investigating the effects of compound paralogous EPHB receptor mutations on mouse facial development.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jul 2022
Mincer Sarah T, Niethamer Terren K, Teng Teng, Bush Jeffrey O, Percival Christopher J
Abstract excerpt
BACKGROUND: Variation in facial shape may arise from the combinatorial or overlapping actions of paralogous genes. Given its many members, and overlapping expression and functions, the EPH receptor family is a compelling candidate source of craniofacial morphological variation. We performed a detailed morphometric analysis of an allelic series of E14.5 Ephb1-3 receptor mutants to determine the effect of each...
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