Article
Ephrin-B1 forward and reverse signaling are required during mouse development.
Genes & development - 1 Mar 2004
Davy Alice, Aubin Josée, Soriano Philippe
Abstract excerpt
Eph receptors and ephrin ligands are key players in many developmental processes including embryo patterning, angiogenesis, and axon guidance. Eph/ephrin interactions lead to the generation of a bidirectional signal, in which both the Eph receptors and the ephrins activate downstream signaling cascades simultaneously. To understand the role of ephrin-B1 and the importance of ephrin-B1-induced reverse signaling...
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