Article
The role of the Eph-ephrin signalling system in the regulation of developmental patterning.
The International journal of developmental biology - 1 Jan 2002
Coulthard Mark G, Duffy Shannon, Down Michelle, Evans Betty, Power Maryanne, Smith Fiona, Stylianou Con, Kleikamp Sabine, Oates Andrew, Lackmann Martin, Burns Gordon F, Boyd Andrew W
Abstract excerpt
The Eph and ephrin system, consisting of fourteen Eph receptor tyrosine kinase proteins and nine ephrin membrane proteins in vertebrates, has been implicated in the regulation of many critical events during development. Binding of cell surface Eph and ephrin proteins results in bi-directional signals, which regulate the cytoskeletal, adhesive and motile properties of the interacting cells. Through these signals...
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