Article
Comparative analysis of embryonic gene expression defines potential interaction sites for Xenopus EphB4 receptors with ephrin-B ligands.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 1999
Helbling P M, Saulnier D M, Robinson V, Christiansen J H, Wilkinson D G, Brändli A W
Abstract excerpt
The Eph family of receptor tyrosine kinases and their ligands, the ephrins, act as signaling molecules regulating the migratory behavior of neurons and neural crest cells, and are implicated in tissue patterning, blood vessel formation, and tumorigenesis. On the basis of structural similarities and overlapping binding specificities, Eph receptors as well as their ligands can be divided into A and B subfamilies...
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