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Article

Control of skeletal patterning by ephrinB1-EphB interactions.

Developmental cell - 1 Aug 2003

Compagni Amelia, Logan Malcolm, Klein Rüdiger, Adams Ralf H

Abstract excerpt

We report that targeted inactivation of the Eph receptor ligand ephrinB1 in mouse caused perinatal lethality, edema, defective body wall closure, and skeletal abnormalities. In the thorax, sternocostal connections were arranged asymmetrically and sternebrae were fused, defects that were phenocopied in EphB2/EphB3 receptor mutants. In the wrist, loss of ephrinB1 led to abnormal cartilage segmentation and the...

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Identifiers

PMID: 12919674
DOI: 10.1016/s1534-5807(03)00198-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Control of skeletal patterning by ephrinB1-EphB interactions.PMID 12919674Read ↗

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The role of the Eph-ephrin signalling system in the regulation of developmental patterning.Semantic proximity Read ↗

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Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome.Semantic proximity Read ↗

Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries.Semantic proximity Read ↗

Aberrant cell segregation in craniofacial primordia and the emergence of facial dysmorphology in craniofrontonasal syndromeSemantic proximity Read ↗

Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs.Semantic proximity Read ↗

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Comparative analysis of embryonic gene expression defines potential interaction sites for Xenopus EphB4 receptors with ephrin-B ligands.Semantic proximity Read ↗

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Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development.Semantic proximity Read ↗

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