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Article

Quantitative trait locus detection using combined linkage/disequilibrium analysis.

Genetic epidemiology - 1 Jan 1999

Almasy L, Williams J T, Dyer T D, Blangero J

Abstract excerpt

We describe an extension of the variance component linkage method that augments identity-by-descent information from relatives with identity-by-state information from unrelated individuals, exploiting disequilibrium to facilitate fine mapping of quantitative trait loci. An advantage of the combined linkage/disequilibrium test is that it detects association only in the presence of linkage and is not biased by...

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PMID: 10597408
DOI: 10.1002/gepi.1370170706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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